Volume 20, No. 3, 2023
The Effect Of Acute Consumption Of Energy Drink On Hepatic Function In Male Wistar Rats
Ezeokafor, Emmanuel Nonso , Uchefuna, Roy Chinwuba , Azuoma, Kosisochukwu Emmanuel , Dike, Charles Chijioke , Ndubuisi, Nonso Richard , Onwuka, Kelechi Collins , Ebisintei, Precious , Ike, Chibueze Jeremiah , Enendu, Chika Angela , Eze, Anthonia kanayo
Abstract
The aim of this study is to check the potential health impact associated with excessive consumption of energy drink. Previous studies showed that energy drink contains more caffeine than a cup of coffee and a bottle of coke. Twenty inbreed male wista rats weighing 120-150g were grouped into 4 groups of 5 animals each. Group A received feed and water only (positive control); group B received 1 ml of Monster Drink; group C 2 ml of Monster Drink; and group D 3 ml of Monster Drink. The administration of Monster Drink was done for 21 days. The result showed a significant (p<0.05) increase in AST level in-group B while group C and D had a significant (p<0.05) decrease when compared to group A. There was a significant (p<0.05) increase in alkaline phosphatase level in group B and D while group C had a significant (p<0.05) decrease when compared to group A. Alanine transaminase result showed a significant (p<0.05) increase in-group B while group C and D had a non-significant (p>0.05) increase when compared to group A. Acute consumption of energy drink (for 21 days) affects the liver enzymes. There was significant increase in groups feed on low dose while those of medium and high doses significantly decreased liver enzymes. Further studies are recommended for the chronic consumption of Energy drink.
Pages: 135-141
Keywords: Energy drink, AST, ALP, ALT, liver enzymes.